BIOIMPRESIÓN 3D

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Resultados 157 resultados LastUpdate Última actualización 28/11/2022 [19:00:00] pdf PDF xls XLS

Solicitudes publicadas en los últimos 30 días / Applications published in the last 30 days



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一种挤出式陶瓷义齿3D打印机

NºPublicación: CN217891276U 25/11/2022

Solicitante:

长沙泽尔顿新材料有限公司

Resumen de: CN217891276U

本实用新型提供一种挤出式陶瓷义齿3D打印机,涉及义齿制造技术领域,包括底板,所述底板上表面对称固定连接有第一安装板,底板右侧表面靠近第一安装板位置固定连接有支撑板,所述支撑板上表面固定安装有第一电机,所述第一电机输出端与第一安装板滑动贯穿。本实用新型中,通过电动伸缩杆控制出料头向下移动,对模具出料制作出义齿,第一电机可以调整出料头在X轴上的位置,第二电机可以调整出料头在Y轴上的位置,通过第一电机和第二电机的配合工作,可以控制出料头调整位置,以方便出料头可以针对不同厚度的位置调整出料速度,避免了因出料不均导致义齿内会形成空洞的问题,提升了制作出义齿的质量。

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仿生人工韧带及其制备方法

NºPublicación: CN115382018A 25/11/2022

Solicitante:

吉林大学

Resumen de: CN115382018A

本发明提供一种仿生人工韧带及其制备方法,属于骨骼韧带修复技术领域。其中,本发明的制备方法包括:形成纤维/基质一体化的自增强韧带支架;在所述自增强韧带支架表面修饰细胞粘附层;在表面修饰后的所述自增强韧带支架端部进行矿化处理,以得到仿生人工韧带。本发明实现了纤维/基质结构的一体化成型,并且保证了纤维增强相与基相之间界面连接与融合度,从而进一步提高材料的力学性能,同时表面修饰的细胞粘附层将有利于成纤维细胞的长入,而末端骨质附着区域的矿化也有利于与周围骨性组织的长入与融合,解决现有人工韧带生物活性差,组织融合度低的缺点,从而增强人工韧带的中远期修复效果。

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基于人源脱细胞基质的生物墨水及其制备方法与应用

NºPublicación: CN115382020A 25/11/2022

Solicitante:

银丰低温医学科技有限公司银丰生物工程集团有限公司

Resumen de: CN115382020A

本发明公开了一种基于人源脱细胞基质的生物墨水及其制备方法与应用,属于3D打印生物墨水制备领域。所述生物墨水由以下组分组成:脱细胞基质,4%~15%;明胶,8%~17.5%;壳聚糖,0.1%~3.5%;琼脂,0.5%~3.5%;余量为水。本发明还公开了该生物墨水的制备方法,以及在制备生物支架中的应用。本发明的生物墨水,将脱细胞基质经过冻干研磨成细粉,作为生物墨水成分直接加入,不需要加入胃蛋白酶等外来物,不需要进行消化处理,粘度适合、可打印性较好。利用本发明的生物墨水制备生物支架时不需要使用光固化打印方式,因此不需要用到有毒的光引发剂,且打印支架经冻干后机械性能较好。具有较好的作为植入性组织工程支架的潜力。

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CONTINUOUS UNLOADING AND PACKAGING SYSTEM FOR PHARMACEUTICAL ADDITIVE MANUFACTURING

NºPublicación: CN115397652A 25/11/2022

Solicitante:

南京三迭纪医药科技有限公司

TW_202138161_A

Resumen de: WO2021164660A1

A high throughput, efficient, and simplified unloading and packaging systems and methods for large-scale production of pharmaceutical units (104) using additive manufacturing. The systems and methods may unload, inspect, package, and trace pharmaceutical units, produced by an additive manufacturing system (900), that are not damaged or deformed. The unloading and packaging system can include one or more unloading and packaging devices(100). The unloading and packaging device can include a modular configuration having modules. Individual modules to be arranged in any relative order, at any location, and with any number in the unloading and packaging device. The flexibility of the modular configuration allows one or more modules to be removed or added at any given time due to, e.g., expansion, downsizing, module repair, module upgrades, etc. High throughput can be achieved by operating unloading and packaging devices independently.

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一种可用于低温沉积3D打印的脱细胞基质及其制备方法和应用

NºPublicación: CN115382023A 25/11/2022

Solicitante:

北京积水潭医院

Resumen de: CN115382023A

本发明公开了一种可用于低温沉积3D打印的脱细胞基质及其制备方法和应用,属于组织工程再生医学领域。本发明提供的脱细胞基质的制备方法,包括如下步骤:(1)将动物组织进行脱细胞处理,得到脱细胞基质匀浆;(2)在所述脱细胞基质匀浆中加入乙酸溶液,搅拌,然后让部分乙酸挥发,得到所述脱细胞基质。本发明制备的脱细胞基质具有剪切变稀性和3D可打印性,可以实现脱细胞基质单一材料的3D打印。

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一种I期临床试验用生物样本密集采样智能管理操作车

NºPublicación: CN115381446A 25/11/2022

Solicitante:

无锡市第九人民医院

Resumen de: CN115381446A

本发明提供一种I期临床试验用生物样本密集采样智能管理操作车,属于样本采集技术领域。该I期临床试验用生物样本密集采样智能管理操作车包括第一存储件、第二存储件、第三存储件以及第四存储件。本发明方便用户按照受试者采样的时间顺序直接获取贴有对应标签和符合温控条件的采样管,并集成有具备温控、暂时存储和智能核对生物样本信息功能的智能样本管架,大幅度地减少用户的工作量,提高用户的工作效率,提升用户的工作质量;第一存储件、第二存储件、第三存储件、第四存储件从左至右依次设置,方便在操作车上整齐摆放物品,方便用户快速找到需要的物品,方便用户在不同的区域上进行不同的工作,互不干扰,提高工作效率和工作质量。

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一种基于桁架结构的3D打印多孔种植体及其制造方法

NºPublicación: CN115381570A 25/11/2022

Solicitante:

江苏万疆高科技有限公司

Resumen de: CN115381570A

本发明提供了一种基于桁架结构的3D打印多孔种植体及其制造方法,种植体包括种植体本体,种植体本体外表面设置有外螺纹,种植体本体内中上部的中心位置开设螺纹孔,种植体本体内靠近下端位置设置空腔,空腔位于螺纹孔下方,空腔内设置空间桁架结构,空腔通过空间桁架结构与种植体本体外部连通。本发明中,利用空间桁架结构能够增加种植体本体的结合面积,从而提高种植体本体的稳定性,避免种植体本体出现晃动甚至脱落的问题,延长了种植体本体的使用寿命。

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Multi-function Oral Appliance

NºPublicación: US2022370173A1 24/11/2022

Solicitante:

FERNANDES AMERICO [CA]

CN_115335003_PA

Resumen de: US2022370173A1

Example embodiments of the present invention provide a multi-function oral appliance, comprising an elastomeric polymer, a hard non-elastic polymer, or a combination of the two fused together; formed using 3D printing or vacuum-forming; configured to engage all or part of the bottom and top teeth such that the lower jaw is advanced, e.g., 8 mm, anterior to its habitual resting position and opened, e.g., 8 mm, from its habitual resting position when the appliance is applied; and configured such that, e.g., 90%, or more, of airflow through the mouth is blocked by the appliance. In some embodiments, the appliance is configured to include gel-wells in the interior of the appliance.

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BIOPRINTER WITH PORTABLE STERILE CHAMBER

NºPublicación: WO2022243583A1 24/11/2022

Solicitante:

ACOSTA JOSE ANTONIO [ES]
ADMINISTRACION GENERAL DE LA COMUNIDAD AUTONOMA DE EUSKADI [ES]
FUNDACION UNIV SAN ANTONIO UCAM [ES]

Resumen de: WO2022243583A1

The invention relates to a bioprinter with a portable sterile chamber (1), the sterile working area of which does not cover the entire set of elements that make it up, but instead is confined to the inside of a closed receptacle, smaller than the machine itself, and which is portable and sterilisable. Said sterile chamber is reversibly and hermetically isolated from the outside by means of an elastic membrane, which is a barrier to microorganisms, spores, non-viable particles, etc. and through which one or more injection nozzles (2) are cleanly inserted. The elasticity and flexibility of the membrane adapts to the movement of the head in the three axes, maintaining watertightness and sterility. The device can be installed in a non- sterile working environment. The invention enables preserving the sterility and the isolation of the unfiltered air of the work environment during the transfer of the produced bioprinted objects.

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Transparent, Fracture-Tough Polymerization Resins For The Production Of Dental Shaped Bodies

NºPublicación: US2022370300A1 24/11/2022

Solicitante:

IVOCLAR VIVADENT AG [LI]

Resumen de: US2022370300A1

Radically polymerizable dental material, which contains at least one ABA or AB block copolymer, preferably at least one monofunctional, radically polymerizable monomer (a) and preferably at least one radically polymerizable urethane di(meth)acrylate telechel (b).

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3D PRINTED STRUCTURALLY SOUND PROSTHETIC SOCKET

NºPublicación: US2022370202A1 24/11/2022

Solicitante:

PREC VALVE & AUTOMATION INC [US]

Resumen de: US2022370202A1

A method for 3D printing a prosthetic socket from a digital model, including printing a solid wall perimeter of the prosthetic socket with a width achieved in a single pass of a printing nozzle, and forming a plurality of stiffener elements proximate a bottom end of the prosthetic socket, as a function of the printing the solid wall perimeter, is provided. Also provided is a 3D printed prosthetic socket including an upper portion, a lower portion configured to be attached to a prosthetic pylon, and a plurality of stiffener elements radially extending from the lower portion, wherein the upper portion, the lower portion, and the plurality of stiffener elements are printed as a solid wall construction comprised of a printing material deposited using only a single pass of a printing nozzle.

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METHOD TO BIOPRINT A PATIENT SPECIFIC BONE GRAFT

NºPublicación: US2022370204A1 24/11/2022

Solicitante:

HARTMAN MICHAEL J [US]

Resumen de: US2022370204A1

A system or method for bioprinting bone graft provides obtaining an image of the patient's oral facial area, and viewed with the image viewing software. A restoratively driven dental implant treatment plan is created to restore the patient's missing dentition. The restoratively driven treatment plan is created. A physical exam, review of a patient's desires and expectations, review of imaging, acquisition and review of patient photographs and intraoral digital impressions. The imaging and digital impressions are aligned, via software to create a virtual representation. The anticipated final implant retained dentures, unitary implant crowns, or implant bridges, are planned to provide optimal esthetic and functional results. Dental implants are then planned for prosthetic anchors. Bone deficiencies are evaluated and if areas of boney deficiency are present, a patient specific bone graft is designed to restore said deficient areas. Once designed, it may be printed via additive manufacturing.

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ENDOPROSTHESIS AND METHOD OF MANUFACTURING AN ENDOPROSTHESIS

NºPublicación: US2022370193A1 24/11/2022

Solicitante:

KARDIOZIS SAS [FR]

BR_112022004370_A2

Resumen de: US2022370193A1

The invention relates to an endoprosthesis (1), in particular a vascular stent or a heart stent, comprising at least one body (3) part. At least one area (5,6) of an outer surface, preferably the whole outer surface, of the at least one body part (3) is provided with thrombogenic fibers (2). The invention further relates to methods of manufacturing endoprostheses (1).

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ARTIFICIAL ESOPHAGEAL STRUCTURE HAVING MULTI-LAYER STRUCTURE USING THREE-DIMENSIONAL BIO-PRINTING, AND MANUFACTURING DEVICE AND MANUFACTURING METHOD THEREFOR

NºPublicación: US2022370189A1 24/11/2022

Solicitante:

WONKWANG UNIV CENTER FOR INDUSTRY ACADEMY COOPERATION [KR]
POSTECH RES AND BUSINESS DEVELOPMENT FOUNDATION [KR]
THE CATHOLIC UNIV OF KOREA INDUSTRY ACADEMI COOPERATION FOUNDATION [KR]

KR_20210037052_PA

Resumen de: US2022370189A1

Disclosed are an artificial esophageal structure having a multi-layer structure using three-dimensional bio-printing, and a manufacturing device and manufacturing method therefor. The artificial esophageal structure having a multi-layer structure according to one embodiment of the present invention comprises: a first layer in the shape of a hollow column and having a circular cross section; a second layer which is disposed inside the first layer and which is a column structure that simulates the mucosal layer of the esophagus; and an interlayer support part which is disposed between the first layer and the second layer and which maintains a gap between the layers, wherein the first layer and second layer each comprise: a plurality of column parts disposed at predetermined intervals; and a plurality of strands formed between the plurality of column parts by a dragging technique, and may have a porous structure due to pores between the plurality of strands.

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CONTROLLING THE SIZE OF 3D PRINTING HYDROGEL OBJECTS USING HYDROPHILIC MONOMERS, HYDROPHOBIC MONOMERS, AND CROSSLINKERS

NºPublicación: US2022370188A1 24/11/2022

Solicitante:

LUNG BIOTECHNOLOGY PBC [US]

WO_2022236030_PA

Resumen de: US2022370188A1

The present disclosure provides printable compositions comprising: about 1 weight percent (wt %) to about 40 wt % of one or more hydrophilic monomers; a swelling control agent selected from a hydrophobic monomer, a short chain crosslinker, or a combination thereof; about 0.01 wt % to about 2 wt % of a photo initiator; and 0 wt % to about 75 wt % of a vehicle comprising a protic solvent, by weight of the printable composition. The disclosure also includes methods of use and manufacture related to printable compositions.

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SENSOR CHIP AND METHODS THEREOF

NºPublicación: US2022373562A1 24/11/2022

Solicitante:

NATIONAL UNIV OF SINGAPORE [SG]

JP_2022519067_A

Resumen de: US2022373562A1

The present disclosure relates generally to a sensor chip and methods for the detection of an analyte. In particular, the disclosure relates to a sensor chip for detecting an analyte in a subject suffering from a neurodegenerative disease. The sensor chip comprises a conductive layer on a membrane support layer, wherein a plurality of apertures extend through the conductive layer and the membrane support layer and are arranged such that illumination of the conductive layer and/or the membrane support layer produces a surface plasmon resonance.

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TREATMENT OF TEETH BY ALIGNERS

NºPublicación: US2022374119A1 24/11/2022

Solicitante:

ALIGN TECH INC [US]

ES_2869673_T3

Resumen de: US2022374119A1

A method for treating a subject's teeth. A target configuration for the subject's teeth is determined. Receiving features are produced on a dental base in response to the target configuration, the receiving features being configured to receive physical tooth models. The physical tooth models are assembled on the dental base to form a physical arch model. A dental aligner is produced using the physical arch model to move the subject's teeth to the target configuration.

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ENDOSCOPY INSTRUMENT

NºPublicación: US2022370058A1 24/11/2022

Solicitante:

PROMEDICA HEALTH SYSTEM INC [US]

Resumen de: US2022370058A1

An endoscopy instrument is configured to be adjustable between a retracted position and an extended position. The endoscopy instrument includes a snare forming a loop extending from a proximate end to a distal end and a plurality of basket wires. Each of the basket wires includes a proximate end coupled to the proximate end of the snare and a distal end coupled to the distal end of the snare. The snare and the plurality of the basket wires cooperate to form a basket portion configured to contract when the endoscopy instrument is adjusted from the extended position towards the retracted position during entry of the basket portion into a tubular member. The contracting of the basket portion aids in grasping an object in need of retrieval from a patient.

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Collagen-based formulations usable as soft tissue fillers and/or implants

NºPublicación: AU2021243961A1 24/11/2022

Solicitante:

COLLPLANT LTD

WO_2021191897_A1

Resumen de: AU2021243961A1

A three-dimensional (3D) biocompatible, degradable soft tissue implant, comprising a bioprinted composite scaffold, the composite scaffold comprising a recombinant human collagen (rhCollagen) and a biocompatible synthetic polymer and features: a porous wall; an inner cavity at least partially enclosed within the porous wall; and at least one injection port that connects the inner cavity with an outer most surface of the scaffold, wherein the injection port has an opening sized to permit insertion of an injection device through the port, processes of preparing same and uses thereof in soft tissue reconstruction are provided. Injectable matrices for use in soft tissue reconstruction, either alone or in combination with the implant are also provided.

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RETAINER FOR AN ORTHODONTIC TREATMENT AND METHOD FOR PRODUCING A RETAINER OF THIS TYPE

NºPublicación: DE102021112795A1 24/11/2022

Solicitante:

CYRON RENE [DE]

Resumen de: WO2022242800A2

A retainer (5) generally consists of a plurality of individual or optionally contiguous double wings (6). Each double wing (6) consists of a middle piece (7) and two wings (8), which laterally adjoin the middle piece and are designed for surface-to-surface adhesive bonding to the peripheral surface of a tooth (1, 2). This middle piece (7) is set, approximately at half the height of the tooth crown, between two teeth (1, 2), where the middle piece extends, as far as possible and sharply, into the gap between the teeth (1, 2). The two wings (8) follow the gingival margin (4) and end approximately in the sagittal plane (9) of a tooth. In order to produce a retainer (5), an electronic image of the intraoral side of a tooth-row contour is captured and said electronic image is used to produce a customized retainer (5), for example by means of a 3D printer or a 3D milling machine, i.e. for example to print or to mill the customized retainer. If the adhesive bond of a double wing (6) loosens over time, the adhesive bond of said double wing can be restored without the entire retainer (5) having to be detached from the teeth (1, 2). If a double wing is damaged or lost, the function of the retainer is substantially maintained even at the affected tooth.

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3D printed shapable fixation device for ankle and foot

NºPublicación: SK992022U1 24/11/2022

Solicitante:

MOLNAR IVAN ING [SK]
MICHAL DAVID ING PHD [SK]

Resumen de: SK992022U1

The 3D printed shapable fixation device for ankle and foot is formed by a body (1) of the main part, the body (6) of the reinforcing part and the body (7) of the sole, which are 2 to 5 millimeters thick and are made of thermoplastic material polylactic acid - PLA, body (1) of the main part and the body (6) of the reinforcing part in the inner surface contains holes (2) with regular spacing and holes (3) for securing with Velcro fasteners, the body (1) of the main part contains holes (4) for inserting rivets and a surface (5) for the foot. It is extruded in the form of a plate by gradually adding layers of the thermoplastic material polylactic acid - PLA, which is pushed in the form of a coil through a heated nozzle and deposited according to paths defined by the software on the 3D printer platform.

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SEMI-STABLE NEAR-FIELD ELECTROSPUN SCAFFOLDS AND METHODS OF MAKING AND USING THE SAME

NºPublicación: WO2022245932A1 24/11/2022

Solicitante:

THE UNIV OF MEMPHIS RESEARCH FOUNDATION [US]

US_2022370191_A1

Resumen de: WO2022245932A1

Methods of producing hybrid fibrous scaffolds are provided. The methods include dissolving a polymer, such as polydioxanone, in a solution, such as 1,1, 1,3,3, 3-hexafluoro-2- propanol (HFP), to form a polymer-containing solution. The method comprises electrically charging the polymer-containing solution. The method comprises writing the polymer-containing solution on a counter electrode or a ground in a grid pattern to form semi-stable fibers comprised of the polymer, the semi-stable fibers vary between bent and straight and forming the hybrid fibrous scaffold. The writing may be performed by a 3D printer. The resulting scaffolds and methods of using the same are also disclosed herein.

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A METHOD TO BIOPRINT A PATIENT SPECIFIC BONE GRAFT

NºPublicación: WO2022245600A2 24/11/2022

Solicitante:

HARTMAN MICHAEL J [US]

US_2022370204_PA

Resumen de: WO2022245600A2

A system or method for bioprinting bone graft provides obtaining an image of the patient's oral facial area, and viewed with the image viewing software. A restoratively driven dental implant treatment plan is created to restore the patient's missing dentition. The restoratively driven treatment plan is created. A physical exam, review of a patient's desires and expectations, review of imaging, acquisition and review of patient photographs and intraoral digital impressions. The imaging and digital impressions are aligned, via software to create a virtual representation. The anticipated final implant retained dentures, unitary implant crowns, or implant bridges, are planned to provide optimal esthetic and functional results. Dental implants are then planned for prosthetic anchors. Bone deficiencies are evaluated and if areas of boney deficiency are present, a patient specific bone graft is designed to restore said deficient areas. Once designed, it may be printed via additive manufacturing.

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RESIN COMPOSITION FOR STEREOLITHOGRAPHY

NºPublicación: US2022371264A1 24/11/2022

Solicitante:

KURARAY NORITAKE DENTAL INC [JP]

Resumen de: US2022371264A1

The present invention provides a resin composition for stereolithography that enables easy stereolithographical fabrication; and that can produce a cured object having desirable strain recovery, desirable toughness, and desirable water resistance. The present invention relates to a resin composition for stereolithography comprising a polymerizable compound (A) whose homopolymer has a glass transition temperature (Tg) of 37° C. or higher; and a photopolymerization initiator (B), and having a tan δ at 37° C. of 0.3 or less after cure.

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METHOD FOR PRODUCING AN IMPLANT FROM A BIOCOMPATIBLE SILICONE

Nº publicación: US2022371229A1 24/11/2022

Solicitante:

NOVATECH SA [FR]

Resumen de: US2022371229A1

In a method for producing an implant from a biocompatible silicone, a 3D mathematical model of an implant to be produced is used to create a 3D model of a casting mold for the implant as a negative. The casting mold is produced from a polymeric material through an additive manufacturing process and coated through vapor deposition of a coating material from the parylene family at least in a region that comes into contact with the biocompatible silicone to be cast. A platinum-catalyzed 2-component thermosetting silicone as the biocompatible silicone for the implant is introduced into a mold cavity of the coated casting mold, with a residence time of the implant in a patient's body of more than 29 days. The casting mold is heated to vulcanize the biocompatible silicone, and after cooling down the vulcanized implant is demolded from the casting mold.

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